Investigating Risk Factor Profiles of Women with Early-Onset Presentation of Obstructive and Non-Obstructive Coronary Artery Syndromes

Heart disease is the leading cause of premature death for women in Canada. Ischemic heart (IHD) categorized as myocardial infarction (MI) with no obstructive coronary artery (MINOCA), ischemia arteries (INOCA), and atherosclerotic (CAD) MI (MI-CAD) or without (non-MI CAD). This study aims to prevalence traditional non-traditional IHD risk factors their relationships (M)INOCA compared MI-CAD non-MI CAD young women. investigated who presented (≤55 years old) confirmed by angiography, are currently enrolled either Leslie Diamond Women’s Health Clinic Registry (WHC) Study Avoid cardioVascular Events BC (SAVEBC). Women final diagnoses SCAD Takotusbo cardiomyopathy were excluded. Univariable regression models applied investigate associations odds (M)INOCA, CAD. A total 241 between 2016-2022 analyzed: 68 INOCA 34 MINOCA from WHC 65 74 SAVEBC. Regression analyses demonstrated that migraines preeclampsia most significant higher likelihood associate relative Conversely, presence dyslipidemia a current previous smoking history had highest There differences factor profiles patients